InterPro domain: IPR012953

General Information

  • Identifier IPR012953
  • Description BOP1, N-terminal domain
  • Number of genes 144
  • Gene duplication stats Loading...
  • Associated GO terms GO:0006364  

Abstract

This domain is found in the N-terminal region of BOP1-like WD40 proteins. Bop1 is a nucleolar protein involved in rRNA processing, thereby controlling the cell cycle [ 1 ]. It is required for the maturation of the 25S and 5.8S ribosomal RNAs. It may serve as an essential factor in ribosome formation that coordinates processing of the spacer regions in pre-rRNA.


1. Interaction of beta-giardin with the Bop1 protein in Giardia lamblia. Parasitol. Res. 98, 138-44

Species distribution

Gene table