InterPro domain: IPR012926

General Information

  • Identifier IPR012926
  • Description Ion channel TACAN/TMEM120B
  • Number of genes 213
  • Gene duplication stats Loading...
  • Associated GO terms GO:0016021  

Abstract

This entry represents a group of transmembrane proteins including TACAN (also known as TMEM120A) and TMEM120B. TACAN is an ion channel that contributes to sensing mechanical pain [ 1 ]. TACAN and TMEM120B may be required for efficient adipogenesis [ 2 ].


1. TACAN Is an Ion Channel Involved in Sensing Mechanical Pain. Cell 180, 956-967.e17
2. TMEM120A and B: Nuclear Envelope Transmembrane Proteins Important for Adipocyte Differentiation. PLoS ONE 10, e0127712

Species distribution

Gene table