InterPro domain: IPR012923

General Information

  • Identifier IPR012923
  • Description Chromosome segregation in meiosis protein 3

Abstract

This entry represents a domain found in a group of proteins, including Csm3 from budding yeasts, Swi3 from fission yeasts and TIPIN from animals. They are involved in DNA replication and the maintenance of replication fork stability [ 1 , 2 , 3 ].


1. Swi1 and Swi3 are components of a replication fork protection complex in fission yeast. Mol. Cell. Biol. 24, 8342-55
2. Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress. Nat. Cell Biol. 14, 966-76
3. Tipin and Timeless form a mutually protective complex required for genotoxic stress resistance and checkpoint function. Proc. Natl. Acad. Sci. U.S.A. 103, 18143-7

Species distribution

Gene table