InterPro domain: IPR012891
General Information
- Identifier IPR012891
- Description GCK
- Number of genes 266
- Gene duplication stats Loading...
Abstract
This domain is found in proteins carrying other domains known to be involved in intracellular signalling pathways (such as IPR001806 ) indicating that it might also be involved in these pathways. It has 4 highly conserved cysteine residues, suggesting that it can bind zinc ions. Moreover, it is found repeated in some members of this family (such as Q9LMF3 ); this may indicate that these domains are able to interact with one another, raising the possibility that this domain mediates heterodimerisation.
Species distribution
Gene table
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