InterPro domain: IPR012488

The region featured in this family is found repeated in a number of plant proteins, some of which are expressed specifically in nodules formed during symbiotic interactions with certain bacterial species]. Some of these proteins are also termed glycine-rich proteins (GRPs), due to the presence of a glycine-rich C-terminal region in their structures [ 1 ]. Bacterial infection is required for the induction of nodule-specific GRP genes, and it is thought that nodule-specific GRPs may play non-redundant roles required at specific stages of nodule development [ 2 ]. Members of this group of proteins may be cytosolic, whereas others are thought to be membrane-associated [ 2 ].

1. Glycine-rich proteins encoded by a nodule-specific gene family are implicated in different stages of symbiotic nodule development in Medicago spp. Mol. Plant Microbe Interact. 15, 922-31
2. The temporal and spatial transcription pattern in root nodules of Vicia faba nodulin genes encoding glycine-rich proteins. Plant Mol. Biol. 33, 113-23