InterPro domain: IPR012417

This domain is found repeated in a number of plant calmodulin-binding proteins (such as Q8W235 , Q84ZT8 and Q8H6X1 ). It is thought to represent a calmodulin-binding domain [ 1 , 2 ]. Binding of the proteins to calmodulin depends on the presence of calcium ions [ 3 , 3 ]. Proteins containing this domain are thought to be involved in various processes, such as plant defence responses [ 3 ] and stolonisation or tuberization [ 3 ].

1. Characterization of a pathogen-induced calmodulin-binding protein: mapping of four Ca2+-dependent calmodulin-binding domains. Plant Mol. Biol. 52, 143-59
2. Isolation and characterization of a novel calmodulin-binding protein from potato. J. Biol. Chem. 277, 4206-14