InterPro domain: IPR012170

General Information

  • Identifier IPR012170
  • Description TFIIH subunit Ssl1/p44

Abstract

This entry represents Ssl1/p44m (also known as GTF2H2), which is a component of the transcription factor TFIIH core (includes XPB, p62, p52, p44, p34) [ 1 ]. TFIIH complex is involved in nucleotide excision repair (NER) of damaged DNA and in RNA transcription by RNA polymerase II [ 2 , 3 ].


1. Reconstitution of TFIIH and requirement of its DNA helicase subunits, Rad3 and Rad25, in the incision step of nucleotide excision repair. J. Biol. Chem. 271, 10821-6
2. RNA polymerase transcription factor IIH holoenzyme from yeast. J. Biol. Chem. 269, 28044-8

Species distribution

Gene table