InterPro domain: IPR012137
General Information
- Identifier IPR012137
- Description Nitrate reductase NADH dependent
- Number of genes 166
- Gene duplication stats Loading...
- Associated GO terms GO:0050464 GO:0006809 GO:0042128
Abstract
This entry represents the NADH dependent nitrate reductase (NR) from plants and fungi, including NIA1 and NIA2 from Arabidopsis. They contain an N-terminal oxidoreductase molybdopterin binding domain and a C-terminal FAD-binding domain. In Arabidopsis, NR-mediated nitric oxide (NO) synthesis is required for ABA-induced stomatal closure [ 1 ]. AtNIA1 is involved in the first step of nitrate assimilation [ 2 , 3 ].
1. A new role for an old enzyme: nitrate reductase-mediated nitric oxide generation is required for abscisic acid-induced stomatal closure in Arabidopsis thaliana. Proc. Natl. Acad. Sci. U.S.A. 99, 16314-8
2. Identification and characterization of a chlorate-resistant mutant of Arabidopsis thaliana with mutations in both nitrate reductase structural genes NIA1 and NIA2. Mol. Gen. Genet. 239, 289-97
3. A new locus (NIA 1) in Arabidopsis thaliana encoding nitrate reductase. EMBO J. 7, 3309-14