InterPro domain: IPR011940
General Information
- Identifier IPR011940
- Description Meiotic recombination protein Dmc1
- Number of genes 106
- Gene duplication stats Loading...
- Associated GO terms GO:0003677 GO:0005634 GO:0007131 GO:0000150
Abstract
Dmc1 is a meiosis-specific RecA homologue [ 1 ]. It is a recombinase required for interhomologue recombination and double-strand break repair during meiosis [ 2 , 2 , 3 , 4 ].
1. A protein complex containing Mei5 and Sae3 promotes the assembly of the meiosis-specific RecA homolog Dmc1. Cell 119, 927-40
2. Tid1/Rdh54 promotes colocalization of rad51 and dmc1 during meiotic recombination. Proc. Natl. Acad. Sci. U.S.A. 97, 10814-9
3. Random chromosome segregation without meiotic arrest in both male and female meiocytes of a dmc1 mutant of Arabidopsis. Plant Cell 11, 1623-34
4. Hop2/Mnd1 acts on two critical steps in Dmc1-promoted homologous pairing. Genes Dev. 21, 1758-66
Species distribution
Gene table
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