InterPro domain: IPR011768
General Information
- Identifier IPR011768
- Description Translation elongation factor P
- Number of genes 122
- Gene duplication stats Loading...
- Associated GO terms GO:0003746 GO:0005737 GO:0006414
Abstract
Members of this family possess translation elongation factor activity. They have been shown to stimulate efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro, possibly indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (by similarity) [ 1 ]. This family does not include members of IPR011897 , an EFP-like protein of certain gammaproteobacteria.
1. Molecular characterization of the prokaryotic efp gene product involved in a peptidyltransferase reaction. Biochimie 79, 7-11
Species distribution
Gene table
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