InterPro domain: IPR011678

General Information

  • Identifier IPR011678
  • Description ER membrane protein complex subunit 1, C-terminal
  • Number of genes 156
  • Gene duplication stats Loading...

Abstract

This entry represents the C-terminal domain of ER membrane protein complex subunit 1.

ER membrane protein complex subunit 1 is a component of the ER membrane protein complex (EMC, composed of EMC1, EMC2, EMC3, EMC4, EMC5 and EMC6). In Saccharomyces cerevisiae, the EMC seems to be required for efficient folding of proteins in the endoplasmic reticulum (ER) [ 1 ].


1. Comprehensive characterization of genes required for protein folding in the endoplasmic reticulum. Science 323, 1693-7

Species distribution

Gene table