InterPro domain: IPR011650

General Information

  • Identifier IPR011650
  • Description Peptidase M20, dimerisation domain
  • Number of genes 1062
  • Gene duplication stats Loading...

Abstract

This domain consists of 4 beta strands and two alpha helices which make up the dimerisation surface of members of the MEROPS peptidase family M20 [ 1 ]. This family includes a range of zinc exopeptidases: carboxypeptidases, dipeptidases and specialised aminopeptidases [ 2 ].


1. Crystal structure of carboxypeptidase G2, a bacterial enzyme with applications in cancer therapy. Structure 5, 337-47
2. Evolutionary families of metallopeptidases. Meth. Enzymol. 248, 183-228

Species distribution

Gene table