InterPro domain: IPR011605

General Information

  • Identifier IPR011605
  • Description NusB antitermination factor
  • Number of genes 117
  • Gene duplication stats Loading...
  • Associated GO terms GO:0006353  

Abstract

The NusB protein is involved in the regulation of rRNA biosynthesisby transcriptional antitermination. The antitermination proteins of Escherichia coli are recruited in the replication cycle of Bacteriophage lambda, where they play an important role in switching from the lysogenic to the lytic cycle. The solution structure indicates that the protein folds into an alpha/alpha-helical topology consisting of six helices; the arginine-rich N terminus appears to be disordered [ 1 ].


1. Solution structure of the antitermination protein NusB of Escherichia coli: a novel all-helical fold for an RNA-binding protein. EMBO J. 17, 4092-100

Species distribution

Gene table

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