InterPro domain: IPR011442

General Information

  • Identifier IPR011442
  • Description TAF6, C-terminal HEAT repeat domain
  • Number of genes 209
  • Gene duplication stats Loading...
  • Associated GO terms GO:0006367  

Abstract

TAF6_C is the C-terminal domain of the TAF6 subunit of the general transcription factor TFIID. The crystal structure reveals the presence of five conserved HEAT repeats. This region is necessary for the complexing together of the subunits TAF5, TAF6 and TAF9 [ 1 ].


1. TFIID TAF6-TAF9 complex formation involves the HEAT repeat-containing C-terminal domain of TAF6 and is modulated by TAF5 protein. J. Biol. Chem. 287, 27580-92

Species distribution

Gene table