InterPro domain: IPR011430

General Information

  • Identifier IPR011430
  • Description Down-regulated-in-metastasis protein
  • Number of genes 135
  • Gene duplication stats Loading...

Abstract

These eukaryotic proteins include DRIM (Down-Regulated In Metastasis) ( O75691 ), which is differentially expressed in metastatic and non-metastatic human breast carcinoma cells [ 1 ]. It is believed to be involved in processing of non-coding RNA [ 2 ].


1. Differential gene expression in mammary carcinoma cell lines: identification of DRIM, a new gene down-regulated in metastasis. Anticancer Res. 18, 1409-21
2. A panoramic view of yeast noncoding RNA processing. Cell 113, 919-33

Species distribution

Gene table