InterPro domain: IPR011400

Eukaryotic translation initiation factor 3 subunit B (EIF3B) is a component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis.EIF3B is considered to be the major scaffolding subunit and interacts with subunits A, G, I, and J [ 1 ]. It contains an RNA recognition motif (RRM) in its N-terminal region [ 2 ].

1. Mass spectrometry reveals modularity and a complete subunit interaction map of the eukaryotic translation factor eIF3. Proc. Natl. Acad. Sci. U.S.A. 105
2. Crystal structure of the RNA recognition motif of yeast translation initiation factor eIF3b reveals differences to human eIF3b. PLoS ONE 5, 18139-44