InterPro domain: IPR011344

General Information

  • Identifier IPR011344
  • Description Single-stranded DNA-binding protein
  • Number of genes 635
  • Gene duplication stats Loading...
  • Associated GO terms GO:0006260   GO:0003697  

Abstract

Single-stranded DNA-binding protein (SSB) plays an important role in DNA replication, recombination and repair. It binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism [ 1 , 2 , 3 , 4 ].


1. SSB as an organizer/mobilizer of genome maintenance complexes. Crit. Rev. Biochem. Mol. Biol. 43, 289-318
2. Regulation of single-stranded DNA binding by the C termini of Escherichia coli single-stranded DNA-binding (SSB) protein. J. Biol. Chem. 285, 17246-52
3. SSB functions as a sliding platform that migrates on DNA via reptation. Cell 146, 222-32
4. Escherichia coli RadD Protein Functionally Interacts with the Single-stranded DNA-binding Protein. J. Biol. Chem. 291, 20779-86

Species distribution

Gene table