InterPro domain: IPR011130

General Information

  • Identifier IPR011130
  • Description SecA, preprotein cross-linking domain
  • Number of genes 214
  • Gene duplication stats Loading...
  • Associated GO terms GO:0016020   GO:0017038  

Abstract

The SecA ATPase is involved in the insertion and retraction of preproteins through the plasma membrane. This domain has been found to cross-link to preproteins, thought to indicate a role in preprotein binding. The pre-protein cross-linking domain is comprised of two sub domains that are inserted within the ATPase domain [ 1 ].


1. Nucleotide control of interdomain interactions in the conformational reaction cycle of SecA. Science 297, 2018-26

Species distribution

Gene table