InterPro domain: IPR011115

General Information

  • Identifier IPR011115
  • Description SecA DEAD-like, N-terminal

Abstract

SecA protein binds to the plasma membrane where it interacts with proOmpA to support translocation of proOmpA through the membrane. SecA protein achieves this translocation, in association with SecY protein, in an ATP-dependent manner [ 1 , 2 ]. This domain represents the N-terminal ATP-dependent helicase domain, which is related to the IPR0011545 .


1. Amino-terminal region of SecA is involved in the function of SecG for protein translocation into Escherichia coli membrane vesicles. J. Biochem. 124, 122-9
2. SecA protein hydrolyzes ATP and is an essential component of the protein translocation ATPase of Escherichia coli. EMBO J. 8, 961-6

Species distribution

Gene table