InterPro domain: IPR011107

This family includes Saccharomyces cerevisiae type 1 protein phosphatase inhibitor Ypi1 [ 1 ] and human protein phosphatase 1 regulatory subunit 11 (Ppp1r11/hcgv), an atypical E3 ubiquitin-protein ligase also known to be a PP1 inhibitor [ 2 , 3 ].

1. Molecular characterization of Ypi1, a novel Saccharomyces cerevisiae type 1 protein phosphatase inhibitor. J. Biol. Chem. 278, 47744-52
2. Identification and characterization of the human HCG V gene product as a novel inhibitor of protein phosphatase-1. Biochemistry 37, 16728-34
3. RING finger E3 ligase PPP1R11 regulates TLR2 signaling and innate immunity. Elife 5