InterPro domain: IPR010935
General Information
- Identifier IPR010935
- Description SMCs flexible hinge
- Number of genes 560
- Gene duplication stats Loading...
- Associated GO terms GO:0005524 GO:0005515 GO:0051276 GO:0005694
Abstract
This entry represents the hinge region of the SMC (Structural Maintenance of Chromosomes) family of proteins. The hinge region is responsible for formation of the DNA interacting dimer. It is also possible that its precise structure is an essential determinant of the specificity of the DNA-protein interaction [ 1 ].
1. Hinge-mediated dimerization of SMC protein is essential for its dynamic interaction with DNA. EMBO J. 21, 5733-44
Species distribution
Gene table
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