InterPro domain: IPR010519

General Information

  • Identifier IPR010519
  • Description Female-specific protein transformer
  • Number of genes 3
  • Gene duplication stats Loading...
  • Associated GO terms GO:0046660   GO:0006397  

Abstract

Tra is a member of the regulatory pathway controlling female somatic sexual differentiation, regulated by Sxl. It activates dsx female-specific splicing by promoting the formation of a splicing enhancer complex which consists of tra, tra2 and sr proteins [ 1 ].


1. Interspecific comparison of the transformer gene of Drosophila reveals an unusually high degree of evolutionary divergence. Genetics 131, 113-28

Species distribution

Gene table