InterPro domain: IPR010369

This entry represents a group of plant-specific proteins, including protein SOSEKI 1-5 from Arabidopsis thaliana and Physcomitrium patens. SOSEKI proteins (SOK1-5) integrate apical-basal and radial organismal axes to localize to polar cell edges and contain a DIX oligomerization domain that resembles that in the animal Dishevelled polarity regulator [ 1 , 2 ].

1. A SOSEKI-based coordinate system interprets global polarity cues in Arabidopsis. Nat Plants 5, 160-166
2. DIX Domain Polymerization Drives Assembly of Plant Cell Polarity Complexes. Cell 180, 427-439.e12