InterPro domain: IPR010357

General Information

  • Identifier IPR010357
  • Description Thioredoxin domain-containing protein 17-like domain
  • Number of genes 125
  • Gene duplication stats Loading...

Abstract

This domain can be found in thioredoxin domain-containing protein 17 (also known as TRP14), which is a highly conserved and ubiquitously expressed oxidoreductase involved in controlling of cellular redox signalling pathways. TXNDC17 has been shown to efficiently reduce l-cystine and can directly reactivate oxidized protein-tyrosine phosphatase PTP1B [ 1 ].


1. Thioredoxin-related protein of 14 kDa as a modulator of redox signalling pathways. Br J Pharmacol 176, 544-553

Species distribution

Gene table