InterPro domain: IPR010233

General Information

  • Identifier IPR010233
  • Description Ubiquinone biosynthesis O-methyltransferase
  • Number of genes 141
  • Gene duplication stats Loading...
  • Associated GO terms GO:0006744   GO:0008425  

Abstract

This entry represents an O-methyltransferase, which is believed to act at two points in the ubiquinone biosynthetic pathway in bacteria (UbiG) and mitochondria (COQ3) [ 1 , 2 ]. A separate methylase (MenG/UbiE) catalyses the single C-methylation step. The most commonly used names for genes in this family do not indicate whether this gene is an O-methyl, or C-methyl transferase.


1. Ubiquinone biosynthesis in microorganisms. FEMS Microbiol. Lett. 203, 131-9
2. Yeast and rat Coq3 and Escherichia coli UbiG polypeptides catalyze both O-methyltransferase steps in coenzyme Q biosynthesis. J. Biol. Chem. 274, 21665-72

Species distribution

Gene table