InterPro domain: IPR010203

General Information

  • Identifier IPR010203
  • Description Regulator of ribonuclease activity A
  • Number of genes 279
  • Gene duplication stats Loading...
  • Associated GO terms GO:0008428   GO:0051252  

Abstract

The regulator of ribonuclease activity A (RraA) family includes a number of closely related sequences from bacteria and plants. The Escherichia coli member has been characterised, and its crystal structure determined [ 1 ]. It acts as a regulator of the endonuclease RNase E [ 2 ] (see IPR004659 ) by binding to it and inhibiting RNA processing [ 3 ].


1. The X-ray structure of Escherichia coli RraA (MenG), A protein inhibitor of RNA processing. J. Mol. Biol. 332, 1015-24
2. RraA. a protein inhibitor of RNase E activity that globally modulates RNA abundance in E. coli. Cell 114, 623-34

Species distribution

Gene table