InterPro domain: IPR009522

This entry represents nucleocapsid proteins from the ssRNA viruses Tenuivirus and Phlebovirus [ 1 , 2 ]. These are ssRNA viruses.

In crystal structures, the nucleocapsid protein from the Rift Valley fever virus (RVFV) displays a ring-shaped oligomeric assembly [ 3 ]. Electron microscopy (EM) also demonstrates that, in complex with RNA, the nucleocapsid protein forms rings in solution [ 4 ].

1. Nucleotide sequence and RNA hybridization analyses reveal an ambisense coding strategy for maize stripe virus RNA3. Virology 182, 47-53
2. Sequences and coding strategies of the S RNAs of Toscana and Rift Valley fever viruses compared to those of Punta Toro, Sicilian Sandfly fever, and Uukuniemi viruses. Virology 180, 738-53
3. Structure of the Rift Valley fever virus nucleocapsid protein reveals another architecture for RNA encapsidation. Proc. Natl. Acad. Sci. U.S.A. 107, 11769-74
4. The hexamer structure of Rift Valley fever virus nucleoprotein suggests a mechanism for its assembly into ribonucleoprotein complexes. PLoS Pathog. 7, e1002030