InterPro domain: IPR009446
General Information
- Identifier IPR009446
- Description Mitochondrial genome maintenance protein Mgm101
- Number of genes 1
- Gene duplication stats Loading...
- Associated GO terms GO:0006281 GO:0000262 GO:0003697 GO:0000002
Abstract
The Mgm101 is a Rad52-type single-stranded annealing protein (SSAP) required for mitochondrial DNA (mtDNA) repair and maintenance. Its C-terminal tail is required for single-stranded DNA binding [ 1 ]. It may also play roles in the replication of the mitochondrial genome and the maintenance of its telomeres [ 2 ].
1. A short carboxyl-terminal tail is required for single-stranded DNA binding, higher-order structural organization, and stability of the mitochondrial single-stranded annealing protein Mgm101. Mol. Biol. Cell 24, 1507-18
2. The structure and DNA-binding properties of Mgm101 from a yeast with a linear mitochondrial genome. Nucleic Acids Res. 44, 2227-39
Species distribution
Gene table
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