InterPro domain: IPR009286
General Information
- Identifier IPR009286
- Description Inositol-pentakisphosphate 2-kinase
- Number of genes 199
- Gene duplication stats Loading...
- Associated GO terms GO:0005524 GO:0035299
Abstract
This is a family of inositol-pentakisphosphate 2-kinases (also known as inositol 1,3,4,5,6-pentakisphosphate 2-kinase, Ins(1,3,4,5,6)P5 2-kinase) and InsP5 2-kinase). This enzyme phosphorylates Ins(1,3,4,5,6)P5 to form Ins(1,2,3,4,5,6)P6 (also known as InsP6 or phytate). InsP6 is involved in many processes such as mRNA export, nonhomologous end-joining, endocytosis and ion channel regulation [ 1 ].
1. Biochemical and functional characterization of inositol 1,3,4,5, 6-pentakisphosphate 2-kinases. J. Biol. Chem. 275, 36575-83
Species distribution
Gene table
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