InterPro domain: IPR009286

General Information

  • Identifier IPR009286
  • Description Inositol-pentakisphosphate 2-kinase
  • Number of genes 199
  • Gene duplication stats Loading...
  • Associated GO terms GO:0005524   GO:0035299  

Abstract

This is a family of inositol-pentakisphosphate 2-kinases (also known as inositol 1,3,4,5,6-pentakisphosphate 2-kinase, Ins(1,3,4,5,6)P5 2-kinase) and InsP5 2-kinase). This enzyme phosphorylates Ins(1,3,4,5,6)P5 to form Ins(1,2,3,4,5,6)P6 (also known as InsP6 or phytate). InsP6 is involved in many processes such as mRNA export, nonhomologous end-joining, endocytosis and ion channel regulation [ 1 ].


1. Biochemical and functional characterization of inositol 1,3,4,5, 6-pentakisphosphate 2-kinases. J. Biol. Chem. 275, 36575-83

Species distribution

Gene table