InterPro domain: IPR008862

General Information

  • Identifier IPR008862
  • Description T-complex 11
  • Number of genes 249
  • Gene duplication stats Loading...

Abstract

This family consists of several eukaryotic T-complex protein 11 (Tcp11) related sequences. Tcp11 is only expressed in fertile adult mammalian testes and is thought to be important in sperm function and fertility. The family also contains the Saccharomyces cerevisiae Sok1 protein which is known to suppress cyclic AMP-dependent protein kinase mutants [ 1 ].


1. Suppression of a yeast cyclic AMP-dependent protein kinase defect by overexpression of SOK1, a yeast gene exhibiting sequence similarity to a developmentally regulated mouse gene. Mol. Cell. Biol. 14, 5619-27

Species distribution

Gene table