InterPro domain: IPR008851
General Information
- Identifier IPR008851
- Description Transcription initiation factor IIF, alpha subunit
- Number of genes 181
- Gene duplication stats Loading...
- Associated GO terms GO:0032968 GO:0003677 GO:0005634 GO:0006367
Abstract
Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) or RNA polymerase II-associating protein 74 (RAP74) is the large subunit of transcription factor IIF (TFIIF), which is essential for accurate initiation and stimulates elongation by RNA polymerase II [ 1 ].
1. A key role for the alpha 1 helix of human RAP74 in the initiation and elongation of RNA chains. J. Biol. Chem. 277, 46998-7003
Species distribution
Gene table
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