InterPro domain: IPR008597

General Information

  • Identifier IPR008597
  • Description Invertebrate-type lysozyme
  • Number of genes 15
  • Gene duplication stats Loading...
  • Associated GO terms GO:0003796  

Abstract

This is a family of invertebrate-type lysozymes [ 1 ]. It includes Destabilase ( 3.5.1.44 ), an endo-epsilon(gamma-Glu)-Lys isopeptidase, which cleaves isopeptide bonds formed by transglutaminase (Factor XIIIa) between glutamine gamma-carboxamide and the epsilon-amino group of lysine [ 2 ].


1. The complete amino acid sequence and enzymatic properties of an i-type lysozyme isolated from the common orient clam (Meretrix lusoria). Biosci. Biotechnol. Biochem. 77, 2269-77
2. Genes from the medicinal leech (Hirudo medicinalis) coding for unusual enzymes that specifically cleave endo-epsilon (gamma-Glu)-Lys isopeptide bonds and help to dissolve blood clots. Mol. Gen. Genet. 253, 20-5

Species distribution

Gene table