InterPro domain: IPR008568

General Information

  • Identifier IPR008568
  • Description ER membrane protein complex subunit 3
  • Number of genes 175
  • Gene duplication stats Loading...
  • Associated GO terms GO:0016020  

Abstract

EMC3 is a subunit if the ER Membrane protein Complex (EMC), which is required for efficient folding of proteins in the endoplasmic reticulum (ER). Loss of the EMC leads to accumulation of misfolded membrane proteins [ 1 ].


1. Comprehensive characterization of genes required for protein folding in the endoplasmic reticulum. Science 323, 1693-7

Species distribution

Gene table