InterPro domain: IPR008504

General Information

  • Identifier IPR008504
  • Description ER membrane protein complex subunit 6

Abstract

This entry represents ER membrane protein complex subunit 6 (Emc6). Emc6 is a component of the ER membrane protein complex (EMC), which is composed of Emc1, Emc2, Emc3, Emc4, Emc5 and Emc6 in budding yeast [ 1 ]. The EMC complex is required for efficient folding of proteins in the ER [ 2 , 2 ].


1. Comprehensive characterization of genes required for protein folding in the endoplasmic reticulum. Science 323, 1693-7
2. Biosynthesis of ionotropic acetylcholine receptors requires the evolutionarily conserved ER membrane complex. Proc. Natl. Acad. Sci. U.S.A. 110, E1055-63

Species distribution

Gene table