InterPro domain: IPR008422
General Information
- Identifier IPR008422
- Description Homeobox KN domain
- Number of genes 2570
- Gene duplication stats Loading...
- Associated GO terms GO:0003677 GO:0006355
Abstract
This entry represents a homeobox transcription factor KN domain conserved fromfungi to human and plants [ 1 ]. Genes encoding these proteins were first identified as TALE homeobox proteins in eukaryotes, (including KNOX and MEIS genes) [ 2 , 2 , 3 ]. They have been classified [ 4 , 5 , 6 ].
1. Expression patterns of class I KNOX and YABBY genes in Ruscus aculeatus (Asparagaceae) with implications for phylloclade homology. Dev. Genes Evol. 217, 363-72
2. A novel homeobox protein which recognizes a TGT core and functionally interferes with a retinoid-responsive motif. J. Biol. Chem. 270, 31178-88
3. Analysis of TALE superclass homeobox genes (MEIS, PBC, KNOX, Iroquois, TGIF) reveals a novel domain conserved between plants and animals. Nucleic Acids Res. 25, 4173-80
4. Comprehensive analysis of animal TALE homeobox genes: new conserved motifs and cases of accelerated evolution. J. Mol. Evol. 65, 137-53
5. A comprehensive classification and evolutionary analysis of plant homeobox genes. Mol. Biol. Evol. 26, 2775-94
6. Homeodomain subtypes and functional diversity. Subcell. Biochem. 52, 95-122