InterPro domain: IPR008189

Ribosomal RNA small subunit methyltransferase I (RsmI) is an S-adenosyl-L-methionine-dependent methyltransferase that catalyses the 2-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA [ 1 ]. It may play a role in fine-tuning the shape and functions of the P-site to increase the translation fidelity [ 2 ]. In vitro, active on the assembled 30S subunit, but not naked 16S rRNA or 70S ribosomes [ 3 ].

1. Structural Insights into the Methylation of C1402 in 16S rRNA by Methyltransferase RsmI. PLoS One 11, e0163816
2. Purification, crystallization and preliminary crystallographic analysis of the 16S rRNA methyltransferase RsmI from Escherichia coli. Acta Crystallogr F Struct Biol Commun 70, 1256-9
3. Fine-tuning of the ribosomal decoding center by conserved methyl-modifications in the Escherichia coli 16S rRNA. Nucleic Acids Res. 38, 1341-52