InterPro domain: IPR007657
General Information
- Identifier IPR007657
- Description Glycosyltransferase 61
- Number of genes 1240
- Gene duplication stats Loading...
- Associated GO terms GO:0016757
Abstract
Glycosyltransferase 61 family members are further processed into a mature form. Proteins in this family includes O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2 (POMGnT2, also known as EOGTL) [ 1 ] and EGF domain-specific O-linked N-acetylglucosamine transferase (EOGT) [ 2 ].
This entry also includes plant beta-(1,2)-xylosyltransferase [ 3 ].
1. SGK196 is a glycosylation-specific O-mannose kinase required for dystroglycan function. Science 341, 896-9
2. The EGF repeat-specific O-GlcNAc-transferase Eogt interacts with notch signaling and pyrimidine metabolism pathways in Drosophila. PLoS ONE 8, e62835
3. Molecular cloning and functional expression of beta1, 2-xylosyltransferase cDNA from Arabidopsis thaliana. FEBS Lett. 472, 105-8