InterPro domain: IPR007568

General Information

  • Identifier IPR007568
  • Description RTA-like protein
  • Number of genes 7
  • Gene duplication stats Loading...
  • Associated GO terms GO:0016021  

Abstract

This family is comprised of fungal proteins with multiple transmembrane regions. RTA1 ( P53047 ) is involved in resistance to 7-aminocholesterol [ 1 ], while RTM1 ( P40113 ) confers resistance to an unknown toxic chemical in molasses [ 2 ]. RSB1 is also a member of this family; it is sphingoid long-chain base transporter [ 3 ].


1. Characterization of the Saccharomyces cerevisiae RTA1 gene involved in 7-aminocholesterol resistance. Curr. Genet. 30, 121-5
2. RTM1: a member of a new family of telomeric repeated genes in yeast. Genetics 140, 945-56
3. Loop 5 region is important for the activity of the long-chain base transporter Rsb1. J. Biochem. 161, 207-213

Species distribution

Gene table