InterPro domain: IPR007525
General Information
- Identifier IPR007525
- Description Coenzyme F420 hydrogenase/dehydrogenase beta subunit, C-terminal
- Number of genes 110
- Gene duplication stats Loading...
Abstract
Coenzyme F420 hydrogenase ( 1.12.99.1 ) reduces the low-potential two-electron acceptor coenzyme F420. This family contains the C-termini of F420 hydrogenase and dehydrogenase beta subunits [ 1 , 2 ]. The C terminus of Methanobacterium formicicum formate dehydrogenase beta chain ( 1.2.1.2 , P06130 ) is also represented in this entry [ 3 ]. This region is often found in association with the 4Fe-4S binding domain ( IPR017896 ), and the N terminus IPR007516 .
1. Cloning, sequence determination, and expression of the genes encoding the subunits of the nickel-containing 8-hydroxy-5-deazaflavin reducing hydrogenase from Methanobacterium thermoautotrophicum delta H. Biochemistry 29, 7237-44
2. The F420H2 dehydrogenase from Methanosarcina mazei is a Redox-driven proton pump closely related to NADH dehydrogenases. J. Biol. Chem. 275, 17968-73
3. Cloning, expression, and nucleotide sequence of the formate dehydrogenase genes from Methanobacterium formicicum. J. Biol. Chem. 261, 12942-7