InterPro domain: IPR007306

General Information

  • Identifier IPR007306
  • Description tRNA A64-2'-O-ribosylphosphate transferase
  • Number of genes 122
  • Gene duplication stats Loading...
  • Associated GO terms GO:0043399   GO:0019988  

Abstract

This entry includes tRNA A64-2'-O-ribosylphosphate transferase Rit1 from budding yeasts. Rit1 is a phospho-ribosyl transferase that exclusively modifies the initiator tRNA (tRNAMet(i)) by the addition of a 2'-O-ribosyl phosphate group to Adenosine 64 [ 1 , 2 ]. This entry also includes the C3F10.06c protein from Schizosaccharomyces pombe.


1. Rit1, a tRNA backbone-modifying enzyme that mediates initiator and elongator tRNA discrimination. Cell 79, 535-46
2. Genetic interactions between a null allele of the RIT1 gene encoding an initiator tRNA-specific modification enzyme and genes encoding translation factors in Saccharomyces cerevisiae. Mol. Gen. Genet. 261, 967-76

Species distribution

Gene table

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