InterPro domain: IPR007075

General Information

  • Identifier IPR007075
  • Description RNA polymerase Rpb1, domain 6

Abstract

RNA polymerases catalyse the DNA dependent polymerisation of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial and chloroplast polymerases). This domain, domain 6, represents a mobile module of the RNA polymerase. Domain 6 forms part of the shelf module [ 1 , 2 ]. This family appears to be specific to the largest subunit of RNA polymerase II.


1. Structural modules of the large subunits of RNA polymerase. Introducing archaebacterial and chloroplast split sites in the beta and beta' subunits of Escherichia coli RNA polymerase. J. Biol. Chem. 271, 27969-74
2. Structural basis of transcription: RNA polymerase II at 2.8 angstrom resolution. Science 292, 1863-76

Species distribution

Gene table