InterPro domain: IPR007064

General Information

  • Identifier IPR007064
  • Description Nmd3, N-terminal
  • Number of genes 221
  • Gene duplication stats Loading...

Abstract

Nmd3 acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit [ 1 , 2 ]. This N-terminal region contains four conserved CXXC motifs that could be metal binding.


1. Coordinated nuclear export of 60S ribosomal subunits and NMD3 in vertebrates. EMBO J. 22, 2841-51
2. Nmd3p is a Crm1p-dependent adapter protein for nuclear export of the large ribosomal subunit. J. Cell Biol. 151, 1057-66

Species distribution

Gene table