InterPro domain: IPR006735

General Information

  • Identifier IPR006735
  • Description Replication termination factor 2
  • Number of genes 140
  • Gene duplication stats Loading...
  • Associated GO terms GO:1902979  

Abstract

Rtf2 is a replication termination factor which mediates replication termination at the site-specific replication barrier Rts1. It stabilizes the replication fork stalled at Rts1 until completion of DNA synthesis by a converging replication fork initiated at a flanking origin [ 1 ].


1. Schizosaccharomyces pombe Rtf2 mediates site-specific replication termination by inhibiting replication restart. Proc. Natl. Acad. Sci. U.S.A. 106, 7927-32

Species distribution

Gene table