InterPro domain: IPR006527
General Information
- Identifier IPR006527
- Description F-box associated domain, type 1
- Number of genes 5288
- Gene duplication stats Loading...
Abstract
This domain occurs in a diverse superfamily of genes in plants. Most examples are found C-terminal to an F-box ( IPR001810 ), a 60 amino acid motif involved in ubiquitination of target proteins to mark them for degradation. Two-hybid experiments support the idea that most members are interchangeable F-box subunits of SCF E3 complexes [ 1 ]. Some members have two copies of this domain.
1. The F-box subunit of the SCF E3 complex is encoded by a diverse superfamily of genes in Arabidopsis. Proc. Natl. Acad. Sci. U.S.A. 99, 11519-24
Species distribution
Gene table
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