InterPro domain: IPR006411

General Information

  • Identifier IPR006411
  • Description Fructose-bisphosphate aldolase, class II, yeast/E. coli subtype
  • Number of genes 3
  • Gene duplication stats Loading...
  • Associated GO terms GO:0006096   GO:0004332  

Abstract

Members of this family are class II examples of the glycolytic enzyme fructose-bisphosphate aldolase (FBA). They represent one of two deeply split, architecturally distinct clades of the family that includes class II fructose-bisphosphate aldolases, tagatose-bisphosphate aldolases, and related uncharacterised proteins. The type A and type B Class II FBPA's differ in the presence and absence of distinct indels in the sequence that result in differing loop lengths in the structures [ 1 ]. This family is well-conserved and includes characterised FBA from Saccharomyces cerevisiae (Baker's yeast),Escherichia coli, and Corynebacterium glutamicum.


1. Fructose-bisphosphate aldolases: an evolutionary history. Trends Biochem. Sci. 17, 110-3

Species distribution

Gene table