InterPro domain: IPR006255
General Information
- Identifier IPR006255
- Description Dihydrolipoamide succinyltransferase
- Number of genes 222
- Gene duplication stats Loading...
- Associated GO terms GO:0004149 GO:0045252 GO:0006099
Abstract
These sequences describe the TCA cycle 2-oxoglutarate system E2 component, dihydrolipoamide succinyltransferase. It is closely related to the pyruvate dehydrogenase E2 component, dihydrolipoamide acetyltransferase. Members include the mitochondrial and Gram-negative bacterial forms. Mycobacterial candidates are highly derived, differ in having and extra copy of the lipoyl-binding domain at the N terminus and are generally excluded from this group of sequences as are all examples of dihydrolipoamide acetyltransferase.
Species distribution
Gene table
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