InterPro domain: IPR005787

General Information

  • Identifier IPR005787
  • Description Threonine dehydratase, biosynthetic
  • Number of genes 179
  • Gene duplication stats Loading...
  • Associated GO terms GO:0009097   GO:0004794  

Abstract

This entry describes a form of threonine dehydratase with two copies of the threonine dehydratase C-terminal domain ( IPR001721 _. Members with known function participate in isoleucine biosynthesis and are inhibited by isoleucine.

Threonine dehydratase ( 4.3.1.19 ) (TDH) catalyzes the dehydratation of threonine into alpha-ketobutarate and ammonia. In Escherichia coli and other microorganisms, two classes of TDH are known to exist. One is involvedin the biosynthesis of isoleucine, the other in hydroxamino acid catabolism.

Species distribution

Gene table