InterPro domain: IPR005578

General Information

  • Identifier IPR005578
  • Description Yif1 family
  • Number of genes 281
  • Gene duplication stats Loading...
  • Associated GO terms GO:0005789   GO:0006888  

Abstract

Yif1 (Yip1 interacting factor) is an integral membrane protein required for membrane fusion of ER derived vesicles [ 1 ]. It also plays a role in the biogenesis of ER derived COPII transport vesicles [ 2 ].


1. The Yip1p.Yif1p complex is required for the fusion competence of endoplasmic reticulum-derived vesicles. J. Biol. Chem. 278, 19878-84
2. Yos1p is a novel subunit of the Yip1p-Yif1p complex and is required for transport between the endoplasmic reticulum and the Golgi complex. Mol. Biol. Cell 16, 1673-83

Species distribution

Gene table