InterPro domain: IPR005495

Members of this family are predicted integral membrane proteins of about 350 amino acids long and containing about 6 transmembrane regions. Characterised members include LptF and LptG, two homologous tandem-encoded permeases of an export ATP transporter for lipopolysaccharide (LPS) assembly in most Gram-negative bacteria [ 1 ].

1. Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli. Proc. Natl. Acad. Sci. U.S.A. 105, 5537-42