InterPro domain: IPR005341

General Information

  • Identifier IPR005341
  • Description Mitochondrial import inner membrane translocase subunit Tim16
  • Number of genes 233
  • Gene duplication stats Loading...
  • Associated GO terms GO:0005744   GO:0030150  

Abstract

This entry represents the mitochondrial import inner membrane translocase subunit Tim16 (also known as Pam16).

Tim16 is the fifth essential subunit of the pre-sequence translocase-associated protein import motor (PAM) [ 1 ]. In Saccharomyces cerevisiae (Baker's yeast), Tim16 is required for preprotein translocation into the matrix, but not for protein insertion into the inner membrane [ 2 ].


1. Pam16 has an essential role in the mitochondrial protein import motor. Nat. Struct. Mol. Biol. 11, 226-33

Species distribution

Gene table