InterPro domain: IPR005341
General Information
- Identifier IPR005341
- Description Mitochondrial import inner membrane translocase subunit Tim16
- Number of genes 233
- Gene duplication stats Loading...
- Associated GO terms GO:0005744 GO:0030150
Abstract
This entry represents the mitochondrial import inner membrane translocase subunit Tim16 (also known as Pam16).
Tim16 is the fifth essential subunit of the pre-sequence translocase-associated protein import motor (PAM) [ 1 ]. In Saccharomyces cerevisiae (Baker's yeast), Tim16 is required for preprotein translocation into the matrix, but not for protein insertion into the inner membrane [ 2 ].
1. Pam16 has an essential role in the mitochondrial protein import motor. Nat. Struct. Mol. Biol. 11, 226-33
Species distribution
Gene table
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